Vaccinations

The evolution of vaccine developments, from small pox to COVID-19

Thu, 2021-04-01 21:00 — mike kraft

https://www.nejm.org/doi/full/10.1056/NEJMp2034334

On the Shoulders of Giants — From Jenner’s Cowpox to mRNA Covid Vaccines

In September 2008, Katalin Karikó, Drew Weissman, and their colleagues at the University of Pennsylvania modified messenger RNA (mRNA) using nucleoside analogues. These modifications stabilized the molecule and eliminated its capacity for inducing innate immunity, thereby making mRNA a promising tool for both gene replacement and vaccination.¹ In December 2020, on the basis of safety and efficacy data generated in two large, placebo-controlled studies, the Food and Drug Administration (FDA) issued emergency use authorizations for two mRNA vaccines for the prevention of Covid-19. Clearance of this hurdle by the first mRNA vaccines represents the most recent in a series of breakthroughs in the realm of viral vaccines, each building on the last and each with a compelling record of disease prevention.

Country / Region Tags:

General Topic Tags:

Problem, Solution, SitRep, or ?:

Other

Read more about The evolution of vaccine developments, from small pox to COVID-19
Log in or register to post comments

ANALYSIS: How richer countries got their vaccine supplies first

Thu, 2021-04-01 12:16 — mike kraft

See How Rich Countries Got to the Front of the Vaccine Line Many low-income nations lacked the means to preorder doses, and their residents have received just 0.1 percent of vaccine shots given worldwide. The New York Times

Country / Region Tags:

General Topic Tags:

Problem, Solution, SitRep, or ?:

Situation Report

Read more about ANALYSIS: How richer countries got their vaccine supplies first
Log in or register to post comments

U.S. COVID-19 vaccine rollout analysis hampered by gaps in state data reporting and technology

Thu, 2021-04-01 11:32 — mike kraft

U.S. COVID-19 vaccine rollout analysis hampered by technology, state data reporting When a dose of a COVID-19 vaccine leaves a U.S. manufacturing plant, its path can be traced all the way to the hospital or clinic representative signing for the shipment at its destination. What happens next is not always clear. Tina Bellon, Rebecca Spalding U.S.

Country / Region Tags:

General Topic Tags:

Problem, Solution, SitRep, or ?:

Situation Report

Read more about U.S. COVID-19 vaccine rollout analysis hampered by gaps in state data reporting and technology
Log in or register to post comments

Overview"Coronavirus international developments briefs

Thu, 2021-04-01 11:20 — mike kraft

Factbox-Latest on the worldwide spread of the coronavirus The World Trade Organization said risks from the uneven roll-out of coronavirus vaccination campaigns and the possible emergence of vaccine-resistant strains clouded the outlook for the global trade in goods, while raising its growth forecast slightly. Reuters Staff U.S.

...

* All health workers in Italy must have coronavirus jabs, the government said, in a potentially controversial move aimed at protecting vulnerable patients and pushing back against ‘no-vax’ sentiment.

Country / Region Tags:

General Topic Tags:

Problem, Solution, SitRep, or ?:

Situation Report

Read more about Overview"Coronavirus international developments briefs
Log in or register to post comments

Europe's vaccine rollout 'unacceptably slow' - WHO

Thu, 2021-04-01 11:06 — mike kraft

Covid: Europe's vaccine rollout 'unacceptably slow' - WHO The WHO says the situation in the wider Europe region is more worrying than it has been in several months. BBC News

The World Health Organization (WHO) has criticised the rollout of coronavirus vaccines in Europe as being "unacceptably slow".

It also says the situation in the region is more worrying than it has been for several months.

Country / Region Tags:

General Topic Tags:

Problem, Solution, SitRep, or ?:

Situation Report

Read more about Europe's vaccine rollout 'unacceptably slow' - WHO
Log in or register to post comments

EU reportly seeks 10 million AstraZenca vaccines from India

Thu, 2021-04-01 10:55 — mike kraft

Exclusive: EU seeks 10 million AstraZeneca vaccines from India to meet shortfall - Indian source The European Union has asked India to allow it to buy 10 million doses of AstraZeneca's COVID-19 vaccine from Serum Institute of India, a government official told Reuters, the latest sign of growing pressure on Delhi to export more of its production to other countries. Neha Arora U.S.

Country / Region Tags:

General Topic Tags:

Problem, Solution, SitRep, or ?:

Situation Report

Read more about EU reportly seeks 10 million AstraZenca vaccines from India
Log in or register to post comments

AstraZeneca vaccine: Status report on which countries are using and which ones are suspending

Thu, 2021-04-01 10:42 — mike kraft

Factbox: Some countries limit AstraZeneca vaccine use amid concern over rare blood clots Some countries are restricting use of the AstraZeneca vaccine against COVID-19 while others have resumed inoculations, as investigations into reports of rare, and sometimes severe, blood clots continue. Reuters Staff U.S.

Country / Region Tags:

General Topic Tags:

Problem, Solution, SitRep, or ?:

Situation Report

Read more about AstraZeneca vaccine: Status report on which countries are using and which ones are suspending
Log in or register to post comments

Indications that Vaccines Help Some COVID Long-Haulers

Thu, 2021-04-01 10:33 — mike kraft

An estimated 10% to 30% of people who get COVID-19 suffer from lingering symptoms of the disease, or what's known as "long COVID."

Judy Dodd, who lives in New York City, is one of them. She spent nearly a year plagued by headaches, shortness of breath, extreme fatigue and problems with smell, among other symptoms.

She says she worried that this "slog through life" was going to be her new normal.

Everything changed after she got her COVID-19 vaccine.

"I was like a new person, it was the craziest thing ever," says Dodd, referring to how many of her health problems subsided significantly after her second shot.

Country / Region Tags:

General Topic Tags:

Problem, Solution, SitRep, or ?: