Seasonal influenza epidemics impose substantial burdens on health care systems and cause >5 million hospitalizations of adults each year. The current approach to influenza vaccine development requires comprehensive surveillance of circulating strains, which are constantly moving from continent to continent....
... For high-risk individuals, this could provide critical information to inform immediate treatment options, including quickly taking medications like Paxlovid within one week of symptoms to mitigate a severe response.
Pigs are the ideal genetic mixing vessel to generate a human pandemic influenza strain, because they have receptors in their respiratory tracts which both avian and human flu viruses can bind to.
After more than two years of talks, hopes are high of completing an accord by November 15, though the heart of the document—how to share pathogens and vaccines—is set to be worked out later.
This year's headlines on COVID-19 featured new research on COVID-related mortality, post-acute sequelae of infection, vaccine safety, and potential therapeutics.
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